Background Childhood anaemia remains a major public health challenge in low- and middle-income countries (LMICs). While ...

Gene editing has emerged as a powerful approach for targeting the genetic causes of disease, but getting the editing ...

DNA does not float freely in the cell. Instead, it is wrapped around histone proteins to form structures called nucleosomes.

Nearly 1 in 4 patients with atrial fibrillation who experience an ischaemic stroke despite oral anticoagulation have ...

The gene editing treatment targets the relatively common 1717-1G>A splicing mutation, which does not respond to many current CF therapies.

Introduction Reduced exercise performance is common in patients with repaired tetralogy of Fallot (rToF) and relates to ...

Objective Cardiovascular diseases are a leading cause of morbidity and mortality in SLE. In this target population, ...