Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

Researchers have shown that different epigenome proteins can produce distinct gene expression patterns from the same gene, offering new insights into genetic regulation. The findings could help ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

Using CRISPR, multiomics, and machine learning, molecular biologist Larschan unravels the mysteries of the X chromosome.

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

The images show the abdomen of flies in which a specific enhancer region has been modified. Depending on how much and which part of the region is modified, different areas of the pigment pattern ...

Within the realm of genetic regulation, chromatin modifications such as histone methylation and acetylation play pivotal roles in the transcriptional control of genes. Disruptions in these processes ...

A litter of rat pups, exposed to a common “forever chemical” before birth, grew up to act more impulsively and show ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

This is the first detailed study of how and where ORC subunits regulate epigenetics and gene expression in human cells. “This is the first detailed study of how and where ORC regulates epigenetics and ...